Reaction Details Report a problem with these data
Target
Capsid protein
Ligand
BDBM50589438
Substrate
n/a
Meas. Tech.
ChEMBL_2193554 (CHEMBL5105914)
EC50
130±n/a nM
Citation
 Ivanova Bencheva, L; Donnici, L; Ferrante, L; Prandi, A; Sinisi, R; De Matteo, M; Randazzo, P; Conti, M; Di Lucia, P; Bono, E; Giustini, L; Vittoria Orsale, M; Patsilinakos, A; Monteagudo, E; Iannacone, M; Summa, V; Guidotti, LG; De Francesco, R; Di Fabio, R Discovery and antiviral profile of new sulfamoylbenzamide derivatives as HBV capsid assembly modulators. Bioorg Med Chem Lett 73:0 (2022) [PubMed] 
Target
Name:
Capsid protein
Synonyms:
Core antigen
Type:
PROTEIN
Mol. Mass.:
26278.39
Organism:
Hepatitis B virus
Description:
ChEMBL_450484
Residue:
230
Sequence:
MIFVLGGCRHKLVCSPAPCNFFHLCLIISCSCPTVHASKLCLGWLWGMHIDPYKEFGASVELLSFLPSDFFPSIRDLLDTASALYREALESPEHCSPHHTALRQAILCWGELMNLATWVGSNLEDPASRELVVSYVNVNMGLKIRQLLWFHISCLTFGRETVLEYLVSFGVWIRTPPAYRPPNAPILSTLPETTVVRRRGRSPRRRTPSPRRRRSQSPRRRRSQSRESQC
  
Inhibitor
Name:
BDBM50589438
Synonyms:
CHEMBL5179943
Type:
Small organic molecule
Emp. Form.:
C14H12F3N3O3S
Mol. Mass.:
359.324
SMILES:
Nc1ccc(cc1S(N)(=O)=O)C(=O)Nc1ccc(F)c(c1)C(F)F
Structure:
Search PDB for entries with ligand similarity: