Reaction Details Report a problem with these data
Target
14 kDa phosphohistidine phosphatase
Ligand
BDBM50220832
Substrate
n/a
Meas. Tech.
ChEMBL_2195305 (CHEMBL5107665)
Ki
209000±n/a nM
Citation
 Kim, HJ; Jung, H; Kim, S; Seo, JK; Kee, JM Identification of a Target Site for Covalent Inhibition of Protein Phosphohistidine Phosphatase 1. ACS Med Chem Lett 13:1911-1915 (2022) [PubMed] 
Target
Name:
14 kDa phosphohistidine phosphatase
Synonyms:
3.9.1.3 | PHP | PHP14 | PHP14_HUMAN | PHPT1 | Phosphohistidine phosphatase 1
Type:
PROTEIN
Mol. Mass.:
13830.85
Organism:
Homo sapiens
Description:
ChEMBL_120739
Residue:
125
Sequence:
MAVADLALIPDVDIDSDGVFKYVLIRVHSAPRSGAPAAESKEIVRGYKWAEYHADIYDKVSGDMQKQGCDCECLGGGRISHQSQDKKIHVYGYSMAYGPAQHAISTEKIKAKYPDYEVTWANDGY
  
Inhibitor
Name:
BDBM50220832
Synonyms:
CHEMBL8211 | N-ethylmaleimide
Type:
Small organic molecule
Emp. Form.:
C6H7NO2
Mol. Mass.:
125.1253
SMILES:
CCN1C(=O)C=CC1=O |c:5|
Structure:
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