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Target
Delta-type opioid receptor
Ligand
BDBM50590203
Substrate
n/a
Meas. Tech.
ChEMBL_2195575 (CHEMBL5108091)
Ki
372±n/a nM
Citation
 Sharma, KK; Cassell, RJ; Meqbil, YJ; Su, H; Blaine, AT; Cummins, BR; Mores, KL; Johnson, DK; van Rijn, RM; Altman, RA Modulating ?-arrestin 2 recruitment at the ?- and ?-opioid receptors using peptidomimetic ligands. RSC Med Chem 12:1958-1967 (2021) [PubMed] 
Target
Name:
Delta-type opioid receptor
Synonyms:
D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40382.98
Organism:
Homo sapiens (Human)
Description:
Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor.
Residue:
372
Sequence:
MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM50590203
Synonyms:
CHEMBL5177001
Type:
Small organic molecule
Emp. Form.:
C37H44FN5O5
Mol. Mass.:
657.7742
SMILES:
CCC(=O)N(C1CCN(CC1)C(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)C\C=C(/F)[C@@H](N)Cc1ccc(O)cc1)c1ccccc1 |r|
Structure:
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