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Target
Mu-type opioid receptor
Ligand
BDBM50590201
Substrate
n/a
Meas. Tech.
ChEMBL_2195576 (CHEMBL5108092)
Ki
10.0±n/a nM
Citation
 Sharma, KK; Cassell, RJ; Meqbil, YJ; Su, H; Blaine, AT; Cummins, BR; Mores, KL; Johnson, DK; van Rijn, RM; Altman, RA Modulating ?-arrestin 2 recruitment at the ?- and ?-opioid receptors using peptidomimetic ligands. RSC Med Chem 12:1958-1967 (2021) [PubMed] 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44789.51
Organism:
Homo sapiens (Human)
Description:
P35372
Residue:
400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM50590201
Synonyms:
CHEMBL5173456
Type:
Small organic molecule
Emp. Form.:
C30H40FN5O5
Mol. Mass.:
569.6675
SMILES:
CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)C\C=C(/F)[C@@H](N)Cc1ccc(O)cc1 |r|
Structure:
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