Reaction Details Report a problem with these data
Target
Macrophage migration inhibitory factor
Ligand
BDBM50206092
Substrate
n/a
Meas. Tech.
ChEMBL_2208404 (CHEMBL5121353)
Ki
14±n/a nM
Citation
 Das, B; Baidya, ATK; Mathew, AT; Yadav, AK; Kumar, R Structural modification aimed for improving solubility of lead compounds in early phase drug discovery. Bioorg Med Chem 56:0 (2022) [PubMed] 
Target
Name:
Macrophage migration inhibitory factor
Synonyms:
GIF | GLIF | Glycosylation-inhibiting factor | L-dopachrome isomerase | L-dopachrome tautomerase | MIF | MIF/CD74 (Macrophage migration inhibitory factor and HLA-DR antigens-associated invariant chain) | MIF_HUMAN | MMIF | Macrophage migration inhibitory factor | Macrophage migration inhibitory factor (MIF) | Phenylpyruvate tautomerase
Type:
Enzyme
Mol. Mass.:
12478.18
Organism:
Homo sapiens (Human)
Description:
P14174
Residue:
115
Sequence:
MPMFIVNTNVPRASVPDGFLSELTQQLAQATGKPPQYIAVHVVPDQLMAFGGSSEPCALCSLHSIGKIGGAQNRSYSKLLCGLLAERLRISPDRVYINYYDMNAANVGWNNSTFA
  
Inhibitor
Name:
BDBM50206092
Synonyms:
CHEMBL3917143 | US10336721, Example 32 | US10968198, Example 32
Type:
Small organic molecule
Emp. Form.:
C24H15FN4O4
Mol. Mass.:
442.3987
SMILES:
OC(=O)c1cccc(Oc2cccc3nc(ccc23)-c2cn(nn2)-c2ccc(O)c(F)c2)c1
Structure:
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