Reaction Details Report a problem with these data
Target
Adenosine receptor A2a
Ligand
BDBM50140241
Substrate
n/a
Meas. Tech.
ChEMBL_2216591 (CHEMBL5129723)
Kd
77000±n/a nM
Citation
 Shepherd, C; Robinson, S; Berizzi, A; Thompson, LEJ; Bird, L; Culurgioni, S; Varzandeh, S; Rawlins, PB; Olsen, RHJ; Navratilova, IH Surface Plasmon Resonance Screening to Identify Active and Selective Adenosine Receptor Binding Fragments. ACS Med Chem Lett 13:1172-1181 (2022) [PubMed] 
Target
Name:
Adenosine receptor A2a
Synonyms:
A2A adenosine receptor (hA2A) | AA2AR_HUMAN | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44716.46
Organism:
Homo sapiens (Human)
Description:
P29274
Residue:
412
Sequence:
MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNGYALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS
  
Inhibitor
Name:
BDBM50140241
Synonyms:
Allopurinol | Aloral | Aluline 100 | Aluline 300 | BW-56-158 | BW-56158 | CHEBI:40279 | Caplenal | Cosuric | Hamarin 100 | Hamarin 300 | Ledopur | Lopurin | US11161835, Compound Allopurinol | Uricto | Xanthomax-100 | Xanthomax-300 | Zyloprim | Zyloric | Zyloric-300
Type:
Small organic molecule
Emp. Form.:
C5H4N4O
Mol. Mass.:
136.1115
SMILES:
O=c1[nH]cnc2[nH]ncc12
Structure:
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