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Target
Aminopeptidase N
Ligand
BDBM50022572
Substrate
n/a
Meas. Tech.
ChEMBL_325855 (CHEMBL863242)
Ki
10000±n/a nM
Citation
 Yang, KW; Golich, FC; Sigdel, TK; Crowder, MW Phosphinate, sulfonate, and sulfonamidate dipeptides as potential inhibitors of Escherichia coli aminopeptidase N. Bioorg Med Chem Lett 15:5150-3 (2005) [PubMed]  Article 
Target
Name:
Aminopeptidase N
Synonyms:
AMPN_ECOLI | pepN
Type:
PROTEIN
Mol. Mass.:
98894.57
Organism:
Escherichia coli (strain K12)
Description:
ChEMBL_325855
Residue:
870
Sequence:
MTQQPQAKYRHDYRAPDYQITDIDLTFDLDAQKTVVTAVSQAVRHGASDAPLRLNGEDLKLVSVHINDEPWTAWKEEEGALVISNLPERFTLKIINEISPAANTALEGLYQSGDALCTQCEAEGFRHITYYLDRPDVLARFTTKIIADKIKYPFLLSNGNRVAQGELENGRHWVQWQDPFPKPCYLFALVAGDFDVLRDTFTTRSGREVALELYVDRGNLDRAPWAMTSLKNSMKWDEERFGLEYDLDIYMIVAVDFFNMGAMENKGLNIFNSKYVLARTDTATDKDYLDIERVIGHEYFHNWTGNRVTCRDWFQLSLKEGLTVFRDQEFSSDLGSRAVNRINNVRTMRGLQFAEDASPMAHPIRPDMVIEMNNFYTLTVYEKGAEVIRMIHTLLGEENFQKGMQLYFERHDGSAATCDDFVQAMEDASNVDLSHFRRWYSQSGTPIVTVKDDYNPETEQYTLTISQRTPATPDQAEKQPLHIPFAIELYDNEGKVIPLQKGGHPVNSVLNVTQAEQTFVFDNVYFQPVPALLCEFSAPVKLEYKWSDQQLTFLMRHARNDFSRWDAAQSLLATYIKLNVARHQQGQPLSLPVHVADAFRAVLLDEKIDPALAAEILTLPSVNEMAELFDIIDPIAIAEVREALTRTLATELADELLAIYNANYQSEYRVEHEDIAKRTLRNACLRFLAFGETHLADVLVSKQFHEANNMTDALAALSAAVAAQLPCRDALMQEYDDKWHQNGLVMDKWFILQATSPAANVLETVRGLLQHRSFTMSNPNRIRSLIGAFAGSNPAAFHAEDGSGYLFLVEMLTDLNSRNPQVASRLIEPLIRLKRYDAKRQEKMRAALEQLKGLENLSGDLYEKITKALA
  
Inhibitor
Name:
BDBM50022572
Synonyms:
3-[(1-Amino-ethyl)-hydroxy-phosphinoyl]-2-methyl-propionic acid;hydrate | 3-[(1-amino-ethyl)-hydroxy-phosphin | CHEMBL2093127 | CHEMBL49180
Type:
Small organic molecule
Emp. Form.:
C6H14NO4P
Mol. Mass.:
195.1534
SMILES:
CC(CP(O)(O)C(C)=N)C(O)=O
Structure:
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