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Target
Peroxisome proliferator-activated receptor delta
Ligand
BDBM50175262
Substrate
n/a
Meas. Tech.
ChEMBL_328558 (CHEMBL869429)
EC50
>100000±n/a nM
Citation
 Coppola, GM; Damon, RE; Eskesen, JB; France, DS; Paterniti, JR Biological evaluation of 1-alkyl-3-phenylthioureas as orally active HDL-elevating agents. Bioorg Med Chem Lett 16:113-7 (2005) [PubMed]  Article 
Target
Name:
Peroxisome proliferator-activated receptor delta
Synonyms:
NR1C2 | NUC1 | NUCI | Nuclear hormone receptor 1 | Nuclear receptor subfamily 1 group C member 2 | PPAR delta | PPAR-beta | PPARB | PPARD | PPARD_HUMAN | Peroxisome proliferator-activated receptor | Peroxisome proliferator-activated receptor beta | Peroxisome proliferator-activated receptor delta
Type:
Enzyme
Mol. Mass.:
49910.45
Organism:
Homo sapiens (Human)
Description:
Q03181
Residue:
441
Sequence:
MEQPQEEAPEVREEEEKEEVAEAEGAPELNGGPQHALPSSSYTDLSRSSSPPSLLDQLQMGCDGASCGSLNMECRVCGDKASGFHYGVHACEGCKGFFRRTIRMKLEYEKCERSCKIQKKNRNKCQYCRFQKCLALGMSHNAIRFGRMPEAEKRKLVAGLTANEGSQYNPQVADLKAFSKHIYNAYLKNFNMTKKKARSILTGKASHTAPFVIHDIETLWQAEKGLVWKQLVNGLPPYKEISVHVFYRCQCTTVETVRELTEFAKSIPSFSSLFLNDQVTLLKYGVHEAIFAMLASIVNKDGLLVANGSGFVTREFLRSLRKPFSDIIEPKFEFAVKFNALELDDSDLALFIAAIILCGDRPGLMNVPRVEAIQDTILRALEFHLQANHPDAQYLFPKLLQKMADLRQLVTEHAQMMQRIKKTETETSLHPLLQEIYKDMY
  
Inhibitor
Name:
BDBM50175262
Synonyms:
(S)-N-(5-chloro-2-methylphenyl)-2-ethylpiperidine-1-carbothioamide | CHEMBL199490
Type:
Small organic molecule
Emp. Form.:
C15H21ClN2S
Mol. Mass.:
296.859
SMILES:
CC[C@H]1CCCCN1C(=S)Nc1cc(Cl)ccc1C
Structure:
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