Reaction Details Report a problem with these data
Target
Lysophosphatidic acid receptor 2
Ligand
BDBM50176394
Substrate
n/a
Meas. Tech.
ChEMBL_333863 (CHEMBL865901)
EC50
6330±n/a nM
Citation
 Durgam, GG; Tsukahara, R; Makarova, N; Walker, MD; Fujiwara, Y; Pigg, KR; Baker, DL; Sardar, VM; Parrill, AL; Tigyi, G; Miller, DD Synthesis and pharmacological evaluation of second-generation phosphatidic acid derivatives as lysophosphatidic acid receptor ligands. Bioorg Med Chem Lett 16:633-40 (2005) [PubMed]  Article 
Target
Name:
Lysophosphatidic acid receptor 2
Synonyms:
EDG4 | LPA receptor 2 | LPA-2 | LPA2 | LPAR2 | LPAR2_HUMAN | Lysophosphatidic acid receptor 2 | Lysophosphatidic acid receptor Edg-4
Type:
PROTEIN
Mol. Mass.:
39103.44
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1451385
Residue:
351
Sequence:
MVIMGQCYYNETIGFFYNNSGKELSSHWRPKDVVVVALGLTVSVLVLLTNLLVIAAIASNRRFHQPIYYLLGNLAAADLFAGVAYLFLMFHTGPRTARLSLEGWFLRQGLLDTSLTASVATLLAIAVERHRSVMAVQLHSRLPRGRVVMLIVGVWVAALGLGLLPAHSWHCLCALDRCSRMAPLLSRSYLAVWALSSLLVFLLMVAVYTRIFFYVRRRVQRMAEHVSCHPRYRETTLSLVKTVVIILGAFVVCWTPGQVVLLLDGLGCESCNVLAVEKYFLLLAEANSLVNAAVYSCRDAEMRRTFRRLLCCACLRQSTRESVHYTSSAQGGASTRIMLPENGHPLMDSTL
  
Inhibitor
Name:
BDBM50176394
Synonyms:
CHEMBL202361 | octanoic acid (R)-2-octanoyloxy-3-thiophosphonooxy-propyl ester
Type:
Small organic molecule
Emp. Form.:
C19H37O7PS
Mol. Mass.:
440.532
SMILES:
CCCCCCCC(=O)OC[C@H](COP(O)(O)=S)OC(=O)CCCCCCC
Structure:
Search PDB for entries with ligand similarity: