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Target
Lysophosphatidic acid receptor 3
Ligand
BDBM50177334
Substrate
n/a
Meas. Tech.
ChEMBL_329846 (CHEMBL862795)
EC50
692±n/a nM
Citation
 Gududuru, V; Zeng, K; Tsukahara, R; Makarova, N; Fujiwara, Y; Pigg, KR; Baker, DL; Tigyi, G; Miller, DD Identification of Darmstoff analogs as selective agonists and antagonists of lysophosphatidic acid receptors. Bioorg Med Chem Lett 16:451-6 (2005) [PubMed]  Article 
Target
Name:
Lysophosphatidic acid receptor 3
Synonyms:
Edg7 | LPAR3_RAT | Lpa3 | Lpar3 | Lysophosphatidic acid receptor 1/lysophosphatidic acid receptor 3 | Lysophosphatidic acid receptor Edg-7
Type:
PROTEIN
Mol. Mass.:
40307.81
Organism:
Rattus norvegicus
Description:
ChEMBL_329846
Residue:
354
Sequence:
MNECHYDKRMDFFYNRSNTDTADEWTGTKLVIVLCVGTFFCLFIFFSNSLVIAAVITNRKFHFPFYYLLANLAAADFFAGIAYVFLMFNTGPVSKTLTVNRWLLRQGLLDTSLTASLANLLVIAVERHMSIMRMRIHSNLTKKRVTLLILLVWAIAIFMGAVPTLGWNCLCNISACSSLAPIYSRSYLIFWTVSNLLAFFIMVVVYVRIYMYVKRKTNVLSPHTSGSISRRRAPMKLMKTVMTVLGAFVVCWTPGLVVLLLDGLNCKQCNVQHVKRWFLLLALLNSVMNPIIYSYKDEDMYNTMRKMICCAPHDSNAERHPSRIPSTIHSRSDTGSQYLEDSISQGQVCNKSSS
  
Inhibitor
Name:
BDBM50177334
Synonyms:
CHEMBL198406 | potassium O-(2-(6-(4-octylphenyl)hexyl)-1,3-dioxolan-4-yl)methyl O-hydrogenphosphorothioate
Type:
Small organic molecule
Emp. Form.:
C24H40O5PS
Mol. Mass.:
471.611
SMILES:
CCCCCCCCc1ccc(CCCCCCC2OCC(COP(O)([O-])=S)O2)cc1
Structure:
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