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Target
Peroxisome proliferator-activated receptor alpha
Ligand
BDBM50240436
Substrate
n/a
Meas. Tech.
ChEMBL_2244006 (CHEMBL5158216)
EC50
3500±n/a nM
Citation
 Sahin, C; Magomedova, L; Ferreira, TAM; Liu, J; Tiefenbach, J; Alves, PS; Queiroz, FJG; Oliveira, AS; Bhattacharyya, M; Grouleff, J; Nogueira, PCN; Silveira, ER; Moreira, DC; Leite, JRSA; Brand, GD; Uehling, D; Poda, G; Krause, H; Cummins, CL; Romeiro, LAS Phenolic Lipids Derived from Cashew Nut Shell Liquid to Treat Metabolic Diseases. J Med Chem 65:1961-1978 (2022) [PubMed] 
Target
Name:
Peroxisome proliferator-activated receptor alpha
Synonyms:
NR1C1 | Nuclear receptor subfamily 1 group C member 1 | PPAR | PPAR alpha/gamma | PPAR-alpha | PPARA | PPARA_HUMAN | Peroxisome Proliferator-Activated Receptor alpha | Peroxisome proliferator-activated receptor | Peroxisome proliferator-activated receptor alpha (PPAR alpha)
Type:
Enzyme
Mol. Mass.:
52222.08
Organism:
Homo sapiens (Human)
Description:
Q07869
Residue:
468
Sequence:
MVDTESPLCPLSPLEAGDLESPLSEEFLQEMGNIQEISQSIGEDSSGSFGFTEYQYLGSCPGSDGSVITDTLSPASSPSSVTYPVVPGSVDESPSGALNIECRICGDKASGYHYGVHACEGCKGFFRRTIRLKLVYDKCDRSCKIQKKNRNKCQYCRFHKCLSVGMSHNAIRFGRMPRSEKAKLKAEILTCEHDIEDSETADLKSLAKRIYEAYLKNFNMNKVKARVILSGKASNNPPFVIHDMETLCMAEKTLVAKLVANGIQNKEAEVRIFHCCQCTSVETVTELTEFAKAIPGFANLDLNDQVTLLKYGVYEAIFAMLSSVMNKDGMLVAYGNGFITREFLKSLRKPFCDIMEPKFDFAMKFNALELDDSDISLFVAAIICCGDRPGLLNVGHIEKMQEGIVHVLRLHLQSNHPDDIFLFPKLLQKMADLRQLVTEHAQLVQIIKKTESDAALHPLLQEIYRDMY
  
Inhibitor
Name:
BDBM50240436
Synonyms:
2-Hydroxy-6-pentadecyl-benzoic acid | 2-hydroxy-6-pentadecylbenzoic acid | 6-(pentadecenyl)salicylic acid | anacardic acid
Type:
Small organic molecule
Emp. Form.:
C22H36O3
Mol. Mass.:
348.5194
SMILES:
CCCCCCCCCCCCCCCc1cccc(O)c1C(O)=O
Structure:
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