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Target
Beta-2 adrenergic receptor
Ligand
BDBM50595336
Substrate
n/a
Meas. Tech.
ChEMBL_2245806 (CHEMBL5160016)
Kd
0.980000±n/a nM
Citation
 Liang, Q; Zuo, H; Yang, T; Yin, J; Huang, X; Wang, J; Li, Q; Yin, G; Zhao, X Discovery of dual-target ligands binding to beta2-adrenoceptor and cysteinyl-leukotriene receptor for the potential treatment of asthma from natural products derived DNA-encoded library. Eur J Med Chem 233:0 (2022) [PubMed] 
Target
Name:
Beta-2 adrenergic receptor
Synonyms:
ADRB2 | ADRB2R | ADRB2_HUMAN | B2AR | Beta-2 adrenoceptor | Beta-2 adrenoreceptor
Type:
n/a
Mol. Mass.:
46461.69
Organism:
Homo sapiens (Human)
Description:
P07550
Residue:
413
Sequence:
MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQEAINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNTGEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
  
Inhibitor
Name:
BDBM50595336
Synonyms:
METHOXYPHENAMINE | Methoxyphenamine
Type:
Small organic molecule
Emp. Form.:
C11H17NO
Mol. Mass.:
179.2588
SMILES:
CNC(C)Cc1ccccc1OC
Structure:
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