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Target
Translocator protein
Ligand
BDBM50605927
Substrate
n/a
Meas. Tech.
ChEMBL_2253199 (CHEMBL5167409)
Ki
271±n/a nM
Citation
 Sharma, S; Peng, Q; Vadukoot, AK; Aretz, CD; Jensen, AA; Wallick, AI; Dong, X; Hopkins, CR Synthesis and Biological Characterization of a Series of 2-Sulfonamidebenzamides as Allosteric Modulators of MrgX1. ACS Med Chem Lett 13:841-847 (2022) [PubMed] 
Target
Name:
Translocator protein
Synonyms:
BZRP | MBR | Mitochondrial benzodiazepine receptor | PBR | PKBS | Peripheral benzodiazepine receptor-related protein | Peripheral-type benzodiazepine receptor | TSPO | TSPO_HUMAN
Type:
Enzyme
Mol. Mass.:
18834.74
Organism:
Homo sapiens (Human)
Description:
P30536
Residue:
169
Sequence:
MAPPWVPAMGFTLAPSLGCFVGSRFVHGEGLRWYAGLQKPSWHPPHWVLGPVWGTLYSAMGYGSYLVWKELGGFTEKAVVPLGLYTGQLALNWAWPPIFFGARQMGWALVDLLLVSGAAAATTVAWYQVSPLAARLLYPYLAWLAFTTTLNYCVWRDNHGWRGGRRLPE
  
Inhibitor
Name:
BDBM50605927
Synonyms:
CHEMBL5172913
Type:
Small organic molecule
Emp. Form.:
C18H19FN2O4S
Mol. Mass.:
378.418
SMILES:
CCOc1ccc(F)cc1NC(=O)c1ccccc1NS(=O)(=O)C1CC1
Structure:
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