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Target
D(2) dopamine receptor
Ligand
BDBM50197197
Substrate
n/a
Meas. Tech.
ChEMBL_408171 (CHEMBL907725)
Ki
5000±n/a nM
Citation
 Colabufo, NA; Berardi, F; Perrone, R; Rapposelli, S; Digiacomo, M; Balsamo, A Arylmethyloxyphenyl derivatives: small molecules displaying P-glycoprotein inhibition. J Med Chem 49:6607-13 (2006) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2
Type:
Cell-surface receptors
Mol. Mass.:
50647.10
Organism:
Homo sapiens (Human)
Description:
P14416
Residue:
443
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
  
Inhibitor
Name:
BDBM50197197
Synonyms:
2-((2-phenethylphenoxy)methyl)pyridine | 2-{[2-(2-phenylethyl)phenoxy]methyl}pyridine | CHEMBL216198
Type:
Small organic molecule
Emp. Form.:
C20H19NO
Mol. Mass.:
289.371
SMILES:
C(Cc1ccccc1OCc1ccccn1)c1ccccc1
Structure:
Search PDB for entries with ligand similarity: