Reaction Details Report a problem with these data
Target
Carbonic anhydrase 14
Ligand
BDBM26995
Substrate
n/a
Meas. Tech.
ChEMBL_458929 (CHEMBL924948)
Ki
750000±n/a nM
Citation
 Innocenti, A; Vullo, D; Pastorek, J; Scozzafava, A; Pastorekova, S; Nishimori, I; Supuran, CT Carbonic anhydrase inhibitors. Inhibition of transmembrane isozymes XII (cancer-associated) and XIV with anions. Bioorg Med Chem Lett 17:1532-7 (2007) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 14
Synonyms:
CA-XIV | CA14 | CAH14_HUMAN | Carbonate dehydratase XIV | Carbonic Anhydrase XIV | Carbonic anhydrase | Carbonic anhydrase 14 | Carbonic anhydrase 14 (CA XIV) | Carbonic anhydrase XIV (CA XIV)
Type:
Enzyme
Mol. Mass.:
37665.67
Organism:
Homo sapiens (Human)
Description:
Human (cloned) isozyme.
Residue:
337
Sequence:
MLFSALLLEVIWILAADGGQHWTYEGPHGQDHWPASYPECGNNAQSPIDIQTDSVTFDPDLPALQPHGYDQPGTEPLDLHNNGHTVQLSLPSTLYLGGLPRKYVAAQLHLHWGQKGSPGGSEHQINSEATFAELHIVHYDSDSYDSLSEAAERPQGLAVLGILIEVGETKNIAYEHILSHLHEVRHKDQKTSVPPFNLRELLPKQLGQYFRYNGSLTTPPCYQSVLWTVFYRRSQISMEQLEKLQGTLFSTEEEPSKLLVQNYRALQPLNQRMVFASFIQAGSSYTTGEMLSLGVGILVGCLCLLLAVYFIARKIRKKRLENRKSVVFTSAQATTEA
  
Inhibitor
Name:
BDBM26995
Synonyms:
CHEMBL355001 | H2NSO2NH2 | sulfamamide | sulfamide | sulfamoylamine
Type:
n/a
Emp. Form.:
H4N2O2S
Mol. Mass.:
96.109
SMILES:
NS(N)(=O)=O
Structure:
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