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Target
Fatty-acid amide hydrolase 1 [30-579]
Ligand
BDBM26736
Substrate
n/a
Meas. Tech.
ChEMBL_530431 (CHEMBL972196)
IC50
2.1±n/a nM
Citation
 Ortar, G; Cascio, MG; Moriello, AS; Camalli, M; Morera, E; Nalli, M; Di Marzo, V Carbamoyl tetrazoles as inhibitors of endocannabinoid inactivation: a critical revisitation. Eur J Med Chem 43:62-72 (2008) [PubMed]  Article 
Target
Name:
Fatty-acid amide hydrolase 1 [30-579]
Synonyms:
Anandamide amidohydrolase 1 | FAAH1_RAT | Faah | Faah1 | Fatty Acid Amide Hydrolase | Fatty Acid Amide Hydrolic, FAAH | Fatty-acid amide hydrolase (FAAH) | Fatty-acid amide hydrolase 1 | Fatty-acid amide hydrolase 1 (FAAH) | Fatty-acid amide hydrolase 1 (aa 30-579) | Oleamide hydrolase 1
Type:
Single-pass membrane protein; homodimer
Mol. Mass.:
60474.00
Organism:
Rattus norvegicus (rat)
Description:
P97612 (aa 30-579)
Residue:
550
Sequence:
RWTGRQKARGAATRARQKQRASLETMDKAVQRFRLQNPDLDSEALLTLPLLQLVQKLQSGELSPEAVFFTYLGKAWEVNKGTNCVTSYLTDCETQLSQAPRQGLLYGVPVSLKECFSYKGHDSTLGLSLNEGMPSESDCVVVQVLKLQGAVPFVHTNVPQSMLSFDCSNPLFGQTMNPWKSSKSPGGSSGGEGALIGSGGSPLGLGTDIGGSIRFPSAFCGICGLKPTGNRLSKSGLKGCVYGQTAVQLSLGPMARDVESLALCLKALLCEHLFTLDPTVPPLPFREEVYRSSRPLRVGYYETDNYTMPSPAMRRALIETKQRLEAAGHTLIPFLPNNIPYALEVLSAGGLFSDGGRSFLQNFKGDFVDPCLGDLILILRLPSWFKRLLSLLLKPLFPRLAAFLNSMRPRSAEKLWKLQHEIEMYRQSVIAQWKAMNLDVLLTPMLGPALDLNTPGRATGAISYTVLYNCLDFPAGVVPVTTVTAEDDAQMELYKGYFGDIWDIILKKAMKNSVGLPVAVQCVALPWQEELCLRFMREVEQLMTPQKQPS
  
Inhibitor
Name:
BDBM26736
Synonyms:
CHEMBL509860 | LY2183240 | N,N-dimethyl-5-[(4-phenylphenyl)methyl]-1H-1,2,3,4-tetrazole-1-carboxamide
Type:
Small organic molecule
Emp. Form.:
C17H17N5O
Mol. Mass.:
307.3498
SMILES:
CN(C)C(=O)n1nnnc1Cc1ccc(cc1)-c1ccccc1
Structure:
Search PDB for entries with ligand similarity: