Reaction Details Report a problem with these data
Target
Adenosylhomocysteinase
Ligand
BDBM50244094
Substrate
n/a
Meas. Tech.
ChEMBL_554798 (CHEMBL953951)
Ki
12400±n/a nM
Citation
 Kojima, H; Kozaki, A; Iwata, M; Ando, T; Kitade, Y Synthesis of 3',4'-epoxynoraristeromycin analogs for molecular labeling probe of S-adenosyl-l-homocysteine hydrolase. Bioorg Med Chem 16:6575-9 (2008) [PubMed]  Article 
Target
Name:
Adenosylhomocysteinase
Synonyms:
AHCY | Adenosylhomocysteinase | SAHH | SAHH_HUMAN
Type:
PROTEIN
Mol. Mass.:
47714.06
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1507791
Residue:
432
Sequence:
MSDKLPYKVADIGLAAWGRKALDIAENEMPGLMRMRERYSASKPLKGARIAGCLHMTVETAVLIETLVTLGAEVQWSSCNIFSTQDHAAAAIAKAGIPVYAWKGETDEEYLWCIEQTLYFKDGPLNMILDDGGDLTNLIHTKYPQLLPGIRGISEETTTGVHNLYKMMANGILKVPAINVNDSVTKSKFDNLYGCRESLIDGIKRATDVMIAGKVAVVAGYGDVGKGCAQALRGFGARVIITEIDPINALQAAMEGYEVTTMDEACQEGNIFVTTTGCIDIILGRHFEQMKDDAIVCNIGHFDVEIDVKWLNENAVEKVNIKPQVDRYRLKNGRRIILLAEGRLVNLGCAMGHPSFVMSNSFTNQVMAQIELWTHPDKYPVGVHFLPKKLDEAVAEAHLGKLNVKLTKLTEKQAQYLGMSCDGPFKPDHYRY
  
Inhibitor
Name:
BDBM50244094
Synonyms:
9-[(10R,20S,30S,40R)-30,40-Epoxy-20-hydroxy-cyclopentan-10-yl]-9-H-adenine | CHEMBL507668
Type:
Small organic molecule
Emp. Form.:
C10H11N5O2
Mol. Mass.:
233.2266
SMILES:
Nc1ncnc2n(cnc12)[C@@H]1C[C@H]2O[C@H]2[C@H]1O |r|
Structure:
Search PDB for entries with ligand similarity: