Reaction Details Report a problem with these data
Target
Group IID secretory phospholipase A2
Ligand
BDBM50263003
Substrate
n/a
Meas. Tech.
ChEMBL_489273 (CHEMBL990829)
IC50
>1600±n/a nM
Citation
 Oslund, RC; Cermak, N; Gelb, MH Highly specific and broadly potent inhibitors of mammalian secreted phospholipases A2. J Med Chem 51:4708-14 (2008) [PubMed]  Article 
Target
Name:
Group IID secretory phospholipase A2
Synonyms:
PA2GD_MOUSE | Pla2a2 | Pla2g2d | Splash
Type:
PROTEIN
Mol. Mass.:
16175.77
Organism:
Mus musculus
Description:
ChEMBL_489273
Residue:
144
Sequence:
MRLALLCGLLLAGITATQGGLLNLNKMVTHMTGKKAFFSYWPYGCHCGLGGKGQPKDATDWCCQKHDCCYAHLKIDGCKSLTDNYKYSISQGTIQCSDNGSWCERQLCACDKEVALCLKQNLDSYNKRLRYYWRPRCKGKTPAC
  
Inhibitor
Name:
BDBM50263003
Synonyms:
2-(2-ethyl-3-(o-phenylbenzyl)-8-(2-oxopropoxy)indolizin-1-yl)-2-oxoacetamide | CHEMBL514841
Type:
Small organic molecule
Emp. Form.:
C24H22N2O3
Mol. Mass.:
386.4431
SMILES:
CCc1c(C(=O)C(N)=O)c2c(OC)cc3ccccc3c2n1Cc1ccccc1
Structure:
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