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Target
Transcriptional activator protein LuxR
Ligand
BDBM50266164
Substrate
n/a
Meas. Tech.
ChEMBL_543884 (CHEMBL1016859)
IC50
960±n/a nM
Citation
 Geske, GD; Mattmann, ME; Blackwell, HE Evaluation of a focused library of N-aryl L-homoserine lactones reveals a new set of potent quorum sensing modulators. Bioorg Med Chem Lett 18:5978-81 (2008) [PubMed]  Article 
Target
Name:
Transcriptional activator protein LuxR
Synonyms:
LUXS_ALIF1 | luxR
Type:
PROTEIN
Mol. Mass.:
28527.37
Organism:
Vibrio fischeri (strain ATCC 700601 / ES114)
Description:
ChEMBL_543884
Residue:
250
Sequence:
MNIKNINANEKIIDKIKTCNNNKDINQCLSEIAKIIHCEYYLFAIIYPHSIIKPDVSIIDNYPEKWRKYYDDAGLLEYDPVVDYSKSHHSPINWNVFEKKTIKKESPNVIKEAQESGLITGFSFPIHTASNGFGMLSFAHSDKDIYTDSLFLHASTNVPLMLPSLVDNYQKINTTRKKSDSILTKREKECLAWASEGKSTWDISKILGCSERTVTFHLTNTQMKLNTTNRCQSISKAILTGAINCPYLKN
  
Inhibitor
Name:
BDBM50266164
Synonyms:
(S)-2-(4-nitrophenyl)-N-(2-oxotetrahydrofuran-3-yl)acetamide | CHEMBL468791
Type:
Small organic molecule
Emp. Form.:
C12H12N2O5
Mol. Mass.:
264.2341
SMILES:
[O-][N+](=O)c1ccc(CC(=O)N[C@H]2CCOC2=O)cc1 |r|
Structure:
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