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Target
Transcriptional activator protein LuxR
Ligand
BDBM50265814
Substrate
n/a
Meas. Tech.
ChEMBL_543884 (CHEMBL1016859)
IC50
2200±n/a nM
Citation
 Geske, GD; Mattmann, ME; Blackwell, HE Evaluation of a focused library of N-aryl L-homoserine lactones reveals a new set of potent quorum sensing modulators. Bioorg Med Chem Lett 18:5978-81 (2008) [PubMed]  Article 
Target
Name:
Transcriptional activator protein LuxR
Synonyms:
LUXS_ALIF1 | luxR
Type:
PROTEIN
Mol. Mass.:
28527.37
Organism:
Vibrio fischeri (strain ATCC 700601 / ES114)
Description:
ChEMBL_543884
Residue:
250
Sequence:
MNIKNINANEKIIDKIKTCNNNKDINQCLSEIAKIIHCEYYLFAIIYPHSIIKPDVSIIDNYPEKWRKYYDDAGLLEYDPVVDYSKSHHSPINWNVFEKKTIKKESPNVIKEAQESGLITGFSFPIHTASNGFGMLSFAHSDKDIYTDSLFLHASTNVPLMLPSLVDNYQKINTTRKKSDSILTKREKECLAWASEGKSTWDISKILGCSERTVTFHLTNTQMKLNTTNRCQSISKAILTGAINCPYLKN
  
Inhibitor
Name:
BDBM50265814
Synonyms:
(S)-N-(2-oxotetrahydrofuran-3-yl)-3-(4-(trifluoromethyl)phenyl)propanamide | CHEMBL467396
Type:
Small organic molecule
Emp. Form.:
C14H14F3NO3
Mol. Mass.:
301.2611
SMILES:
FC(F)(F)c1ccc(CCC(=O)N[C@H]2CCOC2=O)cc1 |r|
Structure:
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