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Target
Monoglyceride lipase
Ligand
BDBM50274151
Substrate
n/a
Meas. Tech.
ChEMBL_537181 (CHEMBL992557)
Ki
58700±n/a nM
Citation
 Magrioti, V; Naxakis, G; Hadjipavlou-Litina, D; Makriyannis, A; Kokotos, G A novel monoacylglycerol lipase inhibitor with analgesic and anti-inflammatory activity. Bioorg Med Chem Lett 18:5424-7 (2008) [PubMed]  Article 
Target
Name:
Monoglyceride lipase
Synonyms:
MAGL | MGLL_RAT | Mgl2 | Mgll | Monoacylglycerol lipase | Monoglyceride lipase | Monoglyceride lipase (MGL)
Type:
Enzyme
Mol. Mass.:
33505.38
Organism:
Rattus norvegicus (Rat)
Description:
Q8R431
Residue:
303
Sequence:
MPEASSPRRTPQNVPYQDLPHLVNADGQYLFCRYWKPSGTPKALIFVSHGAGEHCGRYDELAQMLKRLDMLVFAHDHVGHGQSEGERMVVSDFQVFVRDLLQHVNTVQKDYPEVPVFLLGHSMGGAISILAAAERPTHFSGMILISPLILANPESASTLKVLAAKLLNFVLPNISLGRIDSSVLSRNKSEVDLYNSDPLICHAGVKVCFGIQLLNAVSRVERAMPRLTLPFLLLQGSADRLCDSKGAYLLMESSPSQDKTLKMYEGAYHVLHKELPEVTNSVLHEINTWVSHRIAVAGARCLP
  
Inhibitor
Name:
BDBM50274151
Synonyms:
CHEMBL473249 | hexadecane-1,2-diamine dihydrochloride
Type:
Small organic molecule
Emp. Form.:
C16H36N2
Mol. Mass.:
256.4704
SMILES:
CCCCCCCCCCCCCCC(N)CN
Structure:
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