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Target
Gag polyprotein
Ligand
BDBM50273880
Substrate
n/a
Meas. Tech.
ChEMBL_536774 (CHEMBL984568)
IC50
3500±n/a nM
Citation
 LaFrate, AL; Gunther, JR; Carlson, KE; Katzenellenbogen, JA Synthesis and biological evaluation of guanylhydrazone coactivator binding inhibitors for the estrogen receptor. Bioorg Med Chem 16:10075-84 (2008) [PubMed]  Article 
Target
Name:
Gag polyprotein
Synonyms:
GAG_AVIER | gag
Type:
PROTEIN
Mol. Mass.:
61664.68
Organism:
Avian erythroblastosis virus (strain ES4)
Description:
ChEMBL_536774
Residue:
555
Sequence:
REEQVTSEQAKFWLGLGGGRVSPPGPECIEKPATERRIDKGEEMGETTVQRDAKMAPEKMATPKTVGTSCYQCGTATGCNCVTASAPPPPYVGSGLYPSLAGAGEQGQGGDTPRGAEQPRAEPGHAGQAPGPALTDWARIREELASTGPPVVAMPVVIKTEGPAWTPLEPEDTRWLDGKHKRKSSQCLVKSSMSGYIPSCLDKDEQCVVCGDKATGYHYRCITCEGCKSFFRRTIQKNLHPTYSCTYDGCCVIDKITRNQCQLCRFKKCISVGMAMDLVLDDSKRVAKRKLIEENRERRRKEEMIKSLQHRPSPSAEEWELIHVVTEAHRSTNAQGSHWKQRRKFLLEDIGQSPMASMLDGDKVDLEAFSEFTKIITPAITRVVDFAKNLPMFSELPCEDQIILLKGCCMEIMSLRAAVRYDPESETLTLSGEMAVKREQLKNGGLGVVSDAIFDLGKSLSAFNLDDTEVALLQAVLLMSSDRTGLICVDKIEKCQESYLLAFEHYINYRKHNIPHFWSKLLMKVADLRMIGAYHASRFLHMKVECPTELSPQEV
  
Inhibitor
Name:
BDBM50273880
Synonyms:
1-Phenoxy-3,4-dihydronaphthalene-2-carboxaldehyde guanylhydrazone | CHEMBL512206
Type:
Small organic molecule
Emp. Form.:
C18H18N4O
Mol. Mass.:
306.3617
SMILES:
[#7]\[#6](-[#7])=[#7]\[#7]=[#6]-[#6]-1=[#6](-[#8]-c2ccccc2)-c2ccccc2-[#6]-[#6]-1 |w:5.5,c:6|
Structure:
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