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Target
Fe(3+)-Zn(2+) purple acid phosphatase
Ligand
BDBM50080269
Substrate
n/a
Meas. Tech.
ChEMBL_560427 (CHEMBL1015430)
pH
6.2±n/a
IC50
>7000000±n/a nM
Comments
extracted
Citation
 McGeary, RP; Vella, P; Mak, JY; Guddat, LW; Schenk, G Inhibition of purple acid phosphatase with alpha-alkoxynaphthylmethylphosphonic acids. Bioorg Med Chem Lett 19:163-6 (2008) [PubMed]  Article 
Target
Name:
Fe(3+)-Zn(2+) purple acid phosphatase
Synonyms:
Iron(III)-zinc(II) purple acid phosphatase | PAP | PPAF_PHAVU
Type:
PROTEIN
Mol. Mass.:
52875.57
Organism:
Phaseolus vulgaris
Description:
ChEMBL_560427
Residue:
459
Sequence:
MGVVKGLLALALVLNVVVVSNGGKSSNFVRKTNKNRDMPLDSDVFRVPPGYNAPQQVHITQGDLVGRAMIISWVTMDEPGSSAVRYWSEKNGRKRIAKGKMSTYRFFNYSSGFIHHTTIRKLKYNTKYYYEVGLRNTTRRFSFITPPQTGLDVPYTFGLIGDLGQSFDSNTTLSHYELSPKKGQTVLFVGDLSYADRYPNHDNVRWDTWGRFTERSVAYQPWIWTAGNHEIEFAPEINETEPFKPFSYRYHVPYEASQSTSPFWYSIKRASAHIIVLSSYSAYGRGTPQYTWLKKELRKVKRSETPWLIVLMHSPLYNSYNHHFMEGEAMRTKFEAWFVKYKVDVVFAGHVHAYERSERVSNIAYKITNGLCTPVKDQSAPVYITIGDAGNYGVIDSNMIQPQPEYSAFREASFGHGMFDIKNRTHAHFSWNRNQDGVAVEADSVWFFNRHWYPVDDST
  
Inhibitor
Name:
BDBM50080269
Synonyms:
1-naphthalenemethylphosphonate | CHEMBL37851 | Naphthalen-1-ylmethyl-phosphonic acid | naphthalen-1-ylmethylphosphonic acid
Type:
Small organic molecule
Emp. Form.:
C11H11O3P
Mol. Mass.:
222.177
SMILES:
OP(O)(=O)Cc1cccc2ccccc12
Structure:
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