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Target
Cannabinoid receptor 1
Ligand
BDBM50254792
Substrate
n/a
Meas. Tech.
ChEMBL_558495 (CHEMBL963901)
IC50
79.9±n/a nM
Citation
 Kim, JY; Seo, HJ; Lee, SH; Jung, ME; Ahn, K; Kim, J; Lee, J Diarylimidazolyl oxadiazole and thiadiazole derivatives as cannabinoid CB1 receptor antagonists. Bioorg Med Chem Lett 19:142-5 (2008) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 1
Synonyms:
Brain-type cannabinoid receptor | CANNABINOID CB1 | CB-R | CB1 | CNR1_RAT | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cnr1 | Skr6
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
52856.55
Organism:
Rattus norvegicus (rat)
Description:
P20272
Residue:
473
Sequence:
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQEKMTAGDNSPLVPAGDTTNITEFYNKSLSSFKENEENIQCGENFMDMECFMILNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFVDFHVFHRKDSPNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCKKLQSVCSDIFPLIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKHANNTASMHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
  
Inhibitor
Name:
BDBM50254792
Synonyms:
2-tert-butyl-5-(1-(4-chlorophenyl)-5-cyclopropyl-2-(2,4-dichlorophenyl)-1H-imidazol-4-yl)-1,3,4-oxadiazole | CHEMBL480792
Type:
Small organic molecule
Emp. Form.:
C24H21Cl3N4O
Mol. Mass.:
487.809
SMILES:
CC(C)(C)c1nnc(o1)-c1nc(-c2ccc(Cl)cc2Cl)n(c1C1CC1)-c1ccc(Cl)cc1
Structure:
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