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Target
Prostaglandin E2 receptor EP1 subtype
Ligand
BDBM50183182
Substrate
n/a
Meas. Tech.
ChEMBL_544158 (CHEMBL1013439)
Ki
31.62±n/a nM
Citation
 Hall, A; Brown, SH; Budd, C; Clayton, NM; Giblin, GM; Goldsmith, P; Hayhow, TG; Hurst, DN; Naylor, A; Anthony Rawlings, D; Scoccitti, T; Wilson, AW; Winchester, WJ Discovery of GSK345931A: An EP(1) receptor antagonist with efficacy in preclinical models of inflammatory pain. Bioorg Med Chem Lett 19:497-501 (2008) [PubMed]  Article 
Target
Name:
Prostaglandin E2 receptor EP1 subtype
Synonyms:
PE2R1_HUMAN | PGE receptor, EP1 subtype | PTGER1 | Prostaglandin E2 receptor | Prostaglandin E2 receptor EP1 subtype | Prostaglandin E2 receptor EP1 subtype (EP1) | Prostanoid EP1 receptor
Type:
Enzyme
Mol. Mass.:
41834.57
Organism:
Homo sapiens (Human)
Description:
P34995
Residue:
402
Sequence:
MSPCGPLNLSLAGEATTCAAPWVPNTSAVPPSGASPALPIFSMTLGAVSNLLALALLAQAAGRLRRRRSAATFLLFVASLLATDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTRPLLHAARVSVARARLALAAVAAVALAVALLPLARVGRYELQYPGTWCFIGLGPPGGWRQALLAGLFASLGLVALLAALVCNTLSGLALLRARWRRRSRRPPPASGPDSRRRWGAHGPRSASASSASSIASASTFFGGSRSSGSARRARAHDVEMVGQLVGIMVVSCICWSPMLVLVALAVGGWSSTSLQRPLFLAVRLASWNQILDPWVYILLRQAVLRQLLRLLPPRAGAKGGPAGLGLTPSAWEASSLRSSRHSGLSHF
  
Inhibitor
Name:
BDBM50183182
Synonyms:
2''-benzyloxy-5''-chloro-[1,1';2',1'']terphenyl-3-carboxylic acid | 2-Benzyloxy-5-chloro-[1,1';2',1'']terphenyl-3''-carboxylic acid | CHEMBL207174
Type:
Small organic molecule
Emp. Form.:
C26H19ClO3
Mol. Mass.:
414.88
SMILES:
OC(=O)c1cccc(c1)-c1ccccc1-c1cc(Cl)ccc1OCc1ccccc1
Structure:
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