Reaction Details Report a problem with these data
Target
Cannabinoid receptor 1
Ligand
BDBM50277196
Substrate
n/a
Meas. Tech.
ChEMBL_540511 (CHEMBL1030615)
Ki
130±n/a nM
Citation
 Goodman, AJ; Ajello, CW; Worm, K; Le Bourdonnec, B; Savolainen, MA; O'Hare, H; Cassel, JA; Stabley, GJ; Dehaven, RN; Labuda, CJ; Koblish, M; Little, PJ; Brogdon, BL; Smith, SA; Dolle, RE CB2 selective sulfamoyl benzamides: optimization of the amide functionality. Bioorg Med Chem Lett 19:309-13 (2008) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 1
Synonyms:
CANN6 | CANNABINOID CB1 | CB-R | CB1 | CNR | CNR1 | CNR1_HUMAN | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cannabinoid receptor 1 (brain)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
52868.96
Organism:
Homo sapiens (Human)
Description:
P21554
Residue:
472
Sequence:
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQEKMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
  
Inhibitor
Name:
BDBM50277196
Synonyms:
4-(2-methyl-5-(2-neopentyl-2H-tetrazol-5-yl)phenylsulfonyl)morpholine | CHEMBL515102
Type:
Small organic molecule
Emp. Form.:
C17H25N5O3S
Mol. Mass.:
379.477
SMILES:
Cc1ccc(cc1S(=O)(=O)N1CCOCC1)-c1nnn(CC(C)(C)C)n1
Structure:
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