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Target
Beta-2 adrenergic receptor
Ligand
BDBM50259205
Substrate
n/a
Meas. Tech.
ChEMBL_498898 (CHEMBL972492)
EC50
>100000±n/a nM
Citation
 Maruyama, T; Onda, K; Hayakawa, M; Seki, N; Takahashi, T; Moritomo, H; Suzuki, T; Matsui, T; Takasu, T; Nagase, I; Ohta, M Synthesis and evaluation of novel phenoxypropanolamine derivatives containing acetanilides as potent and selective beta3-adrenergic receptor agonists. Bioorg Med Chem 17:3283-94 (2009) [PubMed]  Article 
Target
Name:
Beta-2 adrenergic receptor
Synonyms:
ADRB2 | ADRB2R | ADRB2_HUMAN | B2AR | Beta-2 adrenoceptor | Beta-2 adrenoreceptor
Type:
n/a
Mol. Mass.:
46461.69
Organism:
Homo sapiens (Human)
Description:
P07550
Residue:
413
Sequence:
MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQEAINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNTGEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
  
Inhibitor
Name:
BDBM50259205
Synonyms:
(S)-4'-(2-{[2-Hydroxy-3-(carbazol-4-yloxy)propyl]-amino}ethyl)-2-(2-pyridyl)acetanilide | CHEMBL466923
Type:
Small organic molecule
Emp. Form.:
C30H30N4O3
Mol. Mass.:
494.5842
SMILES:
O[C@@H](CNCCc1ccc(NC(=O)Cc2ccccn2)cc1)COc1cccc2[nH]c3ccccc3c12 |r|
Structure:
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