Reaction Details Report a problem with these data
Target
Leukotriene B4 receptor 1
Ligand
BDBM50280289
Substrate
n/a
Meas. Tech.
ChEMBL_99517 (CHEMBL707241)
IC50
31±n/a nM
Citation
 Sofia, MJ; Jackson, WT; SaussyJr., DL; Silbaugh, SA; Froelich, LL; Cockerham, SL; Stengel, PW Ortho-alkoxyphenol leukotriene B4 receptor antagonists Bioorg Med Chem Lett 2:1669-1674 (1992)    Article 
Target
Name:
Leukotriene B4 receptor 1
Synonyms:
BLT | BLT1 | BLTR | CMKRL1 | Chemoattractant receptor-like 1 | G-protein coupled receptor 16 | GPR16 | LT4R1_HUMAN | LTB4-R 1 | LTB4R | Leukotriene B4 R1 | Leukotriene B4 receptor | Leukotriene B4 receptor 1 | P2RY7 | P2Y purinoceptor 7 | P2Y7
Type:
Enzyme Catalytic Domain
Mol. Mass.:
37582.68
Organism:
Homo sapiens (Human)
Description:
Q15722
Residue:
352
Sequence:
MNTTSSAAPPSLGVEFISLLAIILLSVALAVGLPGNSFVVWSILKRMQKRSVTALMVLNLALADLAVLLTAPFFLHFLAQGTWSFGLAGCRLCHYVCGVSMYASVLLITAMSLDRSLAVARPFVSQKLRTKAMARRVLAGIWVLSFLLATPVLAYRTVVPWKTNMSLCFPRYPSEGHRAFHLIFEAVTGFLLPFLAVVASYSDIGRRLQARRFRRSRRTGRLVVLIILTFAAFWLPYHVVNLAEAGRALAGQAAGLGLVGKRLSLARNVLIALAFLSSSVNPVLYACAGGGLLRSAGVGFVAKLLEGTGSEASSTRRGGSLGQTARSGPAALEPGPSESLTASSPLKLNELN
  
Inhibitor
Name:
BDBM50280289
Synonyms:
4-ethyl-2-(4-fluorobenzyloxy)-5-[6-methyl-6-(2H-1,2,3,4-tetraazol-5-yl)heptyloxy]phenol; with sodium ion | CHEMBL47725
Type:
Small organic molecule
Emp. Form.:
C24H30FN4O3
Mol. Mass.:
441.519
SMILES:
CCc1cc(OCc2ccc(F)cc2)c(O)cc1OCCCCCC(C)(C)c1nn[n-]n1
Structure:
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