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Target
Type-1 angiotensin II receptor
Ligand
BDBM50282309
Substrate
n/a
Meas. Tech.
ChEMBL_34651 (CHEMBL649710)
IC50
0.300000±n/a nM
Citation
 Kevin, NJ; Rivero, RA; Greenlee, WJ; Chang, RS; Chen, TB Subtituted phenylthiophene benzoylsulfonamides with potent binding affinity to angiotensin II AT1 and AT2 receptors Bioorg Med Chem Lett 4:189-194 (1994)    Article 
Target
Name:
Type-1 angiotensin II receptor
Synonyms:
AGTR1 | AGTR1_RABIT | ANGIOTENSIN AT1 | Angiotensin II receptor | Angiotensin II type 1a (AT-1a) receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
41009.15
Organism:
RABBIT
Description:
ANGIOTENSIN AT1 AGTR1 RABBIT::P34976
Residue:
359
Sequence:
MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE
  
Inhibitor
Name:
BDBM50282309
Synonyms:
3-[4-(2-Ethyl-5,7-dimethyl-imidazo[4,5-b]pyridin-3-ylmethyl)-phenyl]-5-methyl-thiophene-2-sulfonic acid benzoylamide | CHEMBL58291
Type:
Small organic molecule
Emp. Form.:
C29H28N4O3S2
Mol. Mass.:
544.688
SMILES:
CCc1nc2c(C)cc(C)nc2n1Cc1ccc(cc1)-c1cc(C)sc1S(=O)(=O)NC(=O)c1ccccc1
Structure:
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