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Target
Type-1 angiotensin II receptor
Ligand
BDBM50282328
Substrate
n/a
Meas. Tech.
ChEBML_36947
IC50
160±n/a nM
Citation
 Kim, D; Mantlo, NB; Tata, JR; Fitch, K; Dhanoa, D; Owens, K; Levorse, D; Siegl, PK; Chang, RS; Chen, T; Scheck, S; Zingaro, GJ; Kivlighn, SD; Greenlee, WJ Acidic phenols: a new class of potent nonpeptide angiotensin II receptor antagonists Bioorg Med Chem Lett 4:207-212 (1994)    Article 
Target
Name:
Type-1 angiotensin II receptor
Synonyms:
AGTR1 | AGTR1_RABIT | ANGIOTENSIN AT1 | Angiotensin II receptor | Angiotensin II type 1a (AT-1a) receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
41009.15
Organism:
RABBIT
Description:
ANGIOTENSIN AT1 AGTR1 RABBIT::P34976
Residue:
359
Sequence:
MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE
  
Inhibitor
Name:
BDBM50282328
Synonyms:
2-Ethyl-5,7-dimethyl-3-{4-[2-(2H-tetrazol-5-yl)-phenoxy]-benzyl}-3H-imidazo[4,5-b]pyridine | CHEMBL293846
Type:
Small organic molecule
Emp. Form.:
C24H23N7O
Mol. Mass.:
425.4857
SMILES:
CCc1nc2c(C)cc(C)nc2n1Cc1ccc(Oc2ccccc2-c2nnn[nH]2)cc1
Structure:
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