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Target
Type-1 angiotensin II receptor
Ligand
BDBM50282352
Substrate
n/a
Meas. Tech.
ChEBML_36772
IC50
1600±n/a nM
Citation
 Miyake, K; Matsukura, M; Yoneda, N; Hiroshima, O; Mori, N; Ishihara, H; Musha, T; Matsuoka, T; Shoji, T; Minami, N; Hamano, S; Saito, I Discovery and development of aryl-fused imidazole-based angiotensin II antagonists Bioorg Med Chem Lett 4:213-218 (1994)    Article 
Target
Name:
Type-1 angiotensin II receptor
Synonyms:
AGTR1 | AGTR1_BOVIN | Angiotensin II type 1a (AT-1a) receptor
Type:
PROTEIN
Mol. Mass.:
41107.81
Organism:
Bos taurus
Description:
ChEMBL_36779
Residue:
359
Sequence:
MILNSSTEDGIKRIQDDCPKAGRHNYIFIMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPTIIHRNVFFIENTNITVCAFHYESQNSTLPVGLGLTKNILGFLFPFLIILTSYTLIWKTLKKAYEIQKNKPRKDDIFKIILAIVLFFFFSWVPHQIFTFMDVLIQLGLIRDCKIEDIVDTAMPITICLAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSENGNSSTKKPAPCIEVE
  
Inhibitor
Name:
BDBM50282352
Synonyms:
4-(2-Butyl-benzoimidazol-1-ylmethyl)-2,6-dinitro-phenol | CHEMBL306670
Type:
Small organic molecule
Emp. Form.:
C18H18N4O5
Mol. Mass.:
370.3593
SMILES:
CCCCc1nc2ccccc2n1Cc1cc(c(O)c(c1)[N+]([O-])=O)[N+]([O-])=O
Structure:
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