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Target
Neurotensin receptor type 1
Ligand
BDBM50282577
Substrate
n/a
Meas. Tech.
ChEMBL_144303 (CHEMBL754348)
Kd
300±n/a nM
Citation
 Dood, DS; Kozikowski, AP; Cusack, B; Richelson, E Synthesis of partially non-peptidic neurotensin mimetics Bioorg Med Chem Lett 4:1241-1246 (1994)    Article 
Target
Name:
Neurotensin receptor type 1
Synonyms:
NTR1_RAT | Neurotensin receptor 1 | Ntsr | Ntsr1
Type:
PROTEIN
Mol. Mass.:
47070.64
Organism:
Rattus norvegicus
Description:
ChEMBL_1466612
Residue:
424
Sequence:
MHLNSSVPQGTPGEPDAQPFSGPQSEMEATFLALSLSNGSGNTSESDTAGPNSDLDVNTDIYSKVLVTAIYLALFVVGTVGNSVTAFTLARKKSLQSLQSTVHYHLGSLALSDLLILLLAMPVELYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTLMSRSRTKKFISAIWLASALLAIPMLFTMGLQNRSGDGTHPGGLVCTPIVDTATVKVVIQVNTFMSFLFPMLVISILNTVIANKLTVMVHQAAEQGRVCTVGTHNGLEHSTFNMTIEPGRVQALRHGVLVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTTFLFDFYHYFYMLTNALFYVSSAINPILYNLVSANFRQVFLSTLACLCPGWRHRRKKRPTFSRKPNSMSSNHAFSTSATRETLY
  
Inhibitor
Name:
BDBM50282577
Synonyms:
(S)-2-{(2S,3S)-2-[(S)-2-{[3-(6-Guanidino-hexyl)-7-(5-guanidino-pentyloxy)-1H-indole-2-carbonyl]-amino}-3-(4-hydroxy-phenyl)-propionylamino]-3-methyl-pentanoylamino}-4-methyl-pentanoic acid with di TFA | CHEMBL21448
Type:
Small organic molecule
Emp. Form.:
C43H66N10O7
Mol. Mass.:
835.0469
SMILES:
CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)c1[nH]c2c(OCCCCCNC(N)=N)cccc2c1CCCCCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(O)=O
Structure:
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