Reaction Details Report a problem with these data
Target
Gag-Pol polyprotein [489-587]
Ligand
BDBM50284922
Substrate
n/a
Meas. Tech.
ChEBML_79465
Ki
1.2±n/a nM
Citation
 Randad, RS; Lubkowska, L; Bhat, TN; Munshi, S; Gulnik, SV; Yu, B; Erickson, JW Symmetry-based HIV Protease inhibitors: rational design of 2-methylbenzamides as novel P2/P2′ ligands Bioorg Med Chem Lett 5:1707-1712 (1995)    Article 
Target
Name:
Gag-Pol polyprotein [489-587]
Synonyms:
Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol
Type:
Enzyme Subunit
Mol. Mass.:
10781.16
Organism:
Human immunodeficiency virus type 1
Description:
P04585[489-587]
Residue:
99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
  
Inhibitor
Name:
BDBM50284922
Synonyms:
1N-[1-benzyl-2,3-dihydroxy-4-(3-hydroxy-2-methylphenylcarboxamido)-5-phenyl-(1S,2R,3S,4S)-pentyl]-3-hydroxy-2-methylbenzamide | CHEMBL299869
Type:
Small organic molecule
Emp. Form.:
C34H36N2O6
Mol. Mass.:
568.6594
SMILES:
Cc1c(O)cccc1C(=O)N[C@@H](Cc1ccccc1)[C@@H](O)[C@@H](O)[C@H](Cc1ccccc1)NC(=O)c1cccc(O)c1C
Structure:
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