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Target
Leukotriene B4 receptor 1
Ligand
BDBM50285072
Substrate
n/a
Meas. Tech.
ChEMBL_98500 (CHEMBL707320)
Ki
11±n/a nM
Citation
 Sofia, MJ; Nelson, K; Herron, DK; Goodson, T; Froelich, LL; Spaethe, SM; Marder, P; Roman, CR; Fleisch, JH 2-alkyl-4-ethyl-5-[6-methyl-6-(2H-tetrazol-5-yl)heptyloxy]phenol leukotriene B4 receptor antagonists Bioorg Med Chem Lett 5:1995-2000 (1995)    Article 
Target
Name:
Leukotriene B4 receptor 1
Synonyms:
BLT | BLT1 | BLTR | CMKRL1 | Chemoattractant receptor-like 1 | G-protein coupled receptor 16 | GPR16 | LT4R1_HUMAN | LTB4-R 1 | LTB4R | Leukotriene B4 R1 | Leukotriene B4 receptor | Leukotriene B4 receptor 1 | P2RY7 | P2Y purinoceptor 7 | P2Y7
Type:
Enzyme Catalytic Domain
Mol. Mass.:
37582.68
Organism:
Homo sapiens (Human)
Description:
Q15722
Residue:
352
Sequence:
MNTTSSAAPPSLGVEFISLLAIILLSVALAVGLPGNSFVVWSILKRMQKRSVTALMVLNLALADLAVLLTAPFFLHFLAQGTWSFGLAGCRLCHYVCGVSMYASVLLITAMSLDRSLAVARPFVSQKLRTKAMARRVLAGIWVLSFLLATPVLAYRTVVPWKTNMSLCFPRYPSEGHRAFHLIFEAVTGFLLPFLAVVASYSDIGRRLQARRFRRSRRTGRLVVLIILTFAAFWLPYHVVNLAEAGRALAGQAAGLGLVGKRLSLARNVLIALAFLSSSVNPVLYACAGGGLLRSAGVGFVAKLLEGTGSEASSTRRGGSLGQTARSGPAALEPGPSESLTASSPLKLNELN
  
Inhibitor
Name:
BDBM50285072
Synonyms:
CHEMBL305560 | sodium 2-butyl-4-ethyl-5-[6-methyl-6-(2H-1,2,3,4-tetraazol-5-yl)heptyloxy]phenol
Type:
Small organic molecule
Emp. Form.:
C21H33N4O2
Mol. Mass.:
373.5129
SMILES:
CCCCc1cc(CC)c(OCCCCCC(C)(C)c2nn[n-]n2)cc1O
Structure:
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