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Target
Delta-type opioid receptor
Ligand
BDBM50286102
Substrate
n/a
Meas. Tech.
ChEBML_53437
IC50
12±n/a nM
Citation
 Husbands, SM; Lewis, JW Morphinan cyclic imines and pyrrolidines containing a constrained phenyl group: High affinity opioid agonists Bioorg Med Chem Lett 5:2969-2974 (1995)    Article 
Target
Name:
Delta-type opioid receptor
Synonyms:
D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40382.98
Organism:
Homo sapiens (Human)
Description:
Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor.
Residue:
372
Sequence:
MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM50286102
Synonyms:
CHEMBL353736 | Morphinan Cyclic Imine analogue
Type:
Small organic molecule
Emp. Form.:
C31H36N2O4
Mol. Mass.:
500.6285
SMILES:
CCOc1ccc(cc1)C1=N[C@@H]2[C@@]3(OC)C=C[C@@]4(C[C@@]13C)C1Cc3ccc(OC)c(O)c3C24CCN1C |c:16,t:10,TLB:6:9:12:32.17.18,20:19:32.11:16.15,9:19:32.11:16.15,16:17:31.23.22:35.33.34,36:35:17:31.23.22,29:31:17:35.33.34|
Structure:
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