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Target
Serine protease 1
Ligand
BDBM50290692
Substrate
n/a
Meas. Tech.
ChEBML_210666
Ki
>1200±n/a nM
Citation
 Quan, ML; Pruitt, JR; Ellis, CD; Liauw, AY; Galemmo, RA; Stouten, PF; Wityak, J; Knabb, RM; Thoolen, MJ; Wong, PC; Wexler, RR Bisbenzamidine isoxazoline derivatives as factor Xa inhibitors Bioorg Med Chem Lett 7:2813-2818 (1997)    Article 
Target
Name:
Serine protease 1
Synonyms:
Alpha-trypsin chain 1 | Alpha-trypsin chain 2 | Beta-trypsin | Cationic trypsinogen | PRSS1 | Serine protease 1 | TRP1 | TRY1 | TRY1_HUMAN | TRYP1 | Thrombin & trypsin | Trypsin | Trypsin I | Trypsin-1
Type:
Enzyme
Mol. Mass.:
26557.80
Organism:
Homo sapiens (Human)
Description:
P07477
Residue:
247
Sequence:
MNPLLILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSLNSGYHFCGGSLINEQWVVSAGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINARVSTISLPTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIKNTIAANS
  
Inhibitor
Name:
BDBM50290692
Synonyms:
CHEMBL433351 | [3-(3-Carbamimidoyl-phenyl)-5-(4-carbamimidoyl-phenylcarbamoyl)-4,5-dihydro-isoxazol-5-yl]-acetic acid
Type:
Small organic molecule
Emp. Form.:
C20H20N6O4
Mol. Mass.:
408.4106
SMILES:
NC(=N)c1ccc(NC(=O)C2(CC(O)=O)CC(=NO2)c2cccc(c2)C(N)=N)cc1 |c:16|
Structure:
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