Reaction Details Report a problem with these data
Target
Leukotriene B4 receptor 1
Ligand
BDBM50291511
Substrate
n/a
Meas. Tech.
ChEBML_98513
IC50
830±n/a nM
Citation
 Greenspan, PD; Main, AJ; Bhagwat, SS; Barsky, LI; Doti, RA; Engle, AR; Frey, LM; Zhou, H; Lipson, KE; Chin, MH; Jackson, RH; Uziel-Fusi, S N-aryl cinnamides: A novel class of rigid and highly potent leukotriene B4 receptor antagonists Bioorg Med Chem Lett 7:949-954 (1997)    Article 
Target
Name:
Leukotriene B4 receptor 1
Synonyms:
BLT | BLT1 | BLTR | CMKRL1 | Chemoattractant receptor-like 1 | G-protein coupled receptor 16 | GPR16 | LT4R1_HUMAN | LTB4-R 1 | LTB4R | Leukotriene B4 R1 | Leukotriene B4 receptor | Leukotriene B4 receptor 1 | P2RY7 | P2Y purinoceptor 7 | P2Y7
Type:
Enzyme Catalytic Domain
Mol. Mass.:
37582.68
Organism:
Homo sapiens (Human)
Description:
Q15722
Residue:
352
Sequence:
MNTTSSAAPPSLGVEFISLLAIILLSVALAVGLPGNSFVVWSILKRMQKRSVTALMVLNLALADLAVLLTAPFFLHFLAQGTWSFGLAGCRLCHYVCGVSMYASVLLITAMSLDRSLAVARPFVSQKLRTKAMARRVLAGIWVLSFLLATPVLAYRTVVPWKTNMSLCFPRYPSEGHRAFHLIFEAVTGFLLPFLAVVASYSDIGRRLQARRFRRSRRTGRLVVLIILTFAAFWLPYHVVNLAEAGRALAGQAAGLGLVGKRLSLARNVLIALAFLSSSVNPVLYACAGGGLLRSAGVGFVAKLLEGTGSEASSTRRGGSLGQTARSGPAALEPGPSESLTASSPLKLNELN
  
Inhibitor
Name:
BDBM50291511
Synonyms:
2-((E)-3-Biphenyl-4-yl-acryloylamino)-benzoic acid | CHEMBL176974
Type:
Small organic molecule
Emp. Form.:
C22H17NO3
Mol. Mass.:
343.3753
SMILES:
OC(=O)c1ccccc1NC(=O)\C=C\c1ccc(cc1)-c1ccccc1
Structure:
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