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Target
Mu-type opioid receptor
Ligand
BDBM50295263
Substrate
n/a
Meas. Tech.
ChEMBL_577734 (CHEMBL1052369)
IC50
7900±n/a nM
Citation
 Torino, D; Mollica, A; Pinnen, F; Lucente, G; Feliciani, F; Davis, P; Lai, J; Ma, SW; Porreca, F; Hruby, VJ Synthesis and evaluation of new endomorphin analogues modified at the Pro(2) residue. Bioorg Med Chem Lett 19:4115-8 (2009) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOR-1 | Mu opioid receptor | Mu-type opioid receptor (Mu) | OPIATE Mu | OPRM1 | OPRM_CAVPO
Type:
Enzyme Catalytic Domain
Mol. Mass.:
11165.58
Organism:
GUINEA PIG
Description:
P97266
Residue:
98
Sequence:
YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI
  
Inhibitor
Name:
BDBM50295263
Synonyms:
(S)-N-((S)-1-((S)-1-amino-1-oxo-3-phenylpropan-2-ylamino)-3-(1H-indol-3-yl)-1-oxopropan-2-yl)-1-((S)-2-amino-3-(4-hydroxyphenyl)propanoyl)azetidine-2-carboxamide | CHEMBL552133
Type:
Small organic molecule
Emp. Form.:
C33H36N6O5
Mol. Mass.:
596.6761
SMILES:
N[C@@H](Cc1ccc(O)cc1)C(=O)N1CC[C@H]1C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1ccccc1)C(N)=O |r|
Structure:
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