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Target
Sialidase-2
Ligand
BDBM50295841
Substrate
n/a
Meas. Tech.
ChEMBL_578462 (CHEMBL1062266)
Ki
307000±n/a nM
Citation
 Magesh, S; Savita, V; Moriya, S; Suzuki, T; Miyagi, T; Ishida, H; Kiso, M Human sialidase inhibitors: design, synthesis, and biological evaluation of 4-acetamido-5-acylamido-2-fluoro benzoic acids. Bioorg Med Chem 17:4595-603 (2009) [PubMed]  Article 
Target
Name:
Sialidase-2
Synonyms:
Cytosolic sialidase | N-acetyl-alpha-neuraminidase 2 | NEU2 | NEUR2_HUMAN | Sialidase 2 | Sialidase-2
Type:
PROTEIN
Mol. Mass.:
42256.20
Organism:
Homo sapiens (Human)
Description:
ChEMBL_960638
Residue:
380
Sequence:
MASLPVLQKESVFQSGAHAYRIPALLYLPGQQSLLAFAEQRASKKDEHAELIVLRRGDYDAPTHQVQWQAQEVVAQARLDGHRSMNPCPLYDAQTGTLFLFFIAIPGQVTEQQQLQTRANVTRLCQVTSTDHGRTWSSPRDLTDAAIGPAYREWSTFAVGPGHCLQLHDRARSLVVPAYAYRKLHPIQRPIPSAFCFLSHDHGRTWARGHFVAQDTLECQVAEVETGEQRVVTLNARSHLRARVQAQSTNDGLDFQESQLVKKLVEPPPQGCQGSVISFPSPRSGPGSPAQWLLYTHPTHSWQRADLGAYLNPRPPAPEAWSEPVLLAKGSCAYSDLQSMGTGPDGSPLFGCLYEANDYEEIVFLMFTLKQAFPAEYLPQ
  
Inhibitor
Name:
BDBM50295841
Synonyms:
4-Acetamido-5-(biphenyl-4-ylcarboxamido)-2-fluorobenzoic acid | CHEMBL559396
Type:
Small organic molecule
Emp. Form.:
C22H17FN2O4
Mol. Mass.:
392.3798
SMILES:
CC(=O)Nc1cc(F)c(cc1NC(=O)c1ccc(cc1)-c1ccccc1)C(O)=O
Structure:
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