Reaction Details Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM50295948
Substrate
n/a
Meas. Tech.
ChEMBL_578989 (CHEMBL1061438)
Ki
3.82±n/a nM
Citation
 Ishiyama, H; Nakajima, H; Nakata, H; Kobayashi, J Synthesis of hybrid analogues of caffeine and eudistomin D and its affinity for adenosine receptors. Bioorg Med Chem 17:4280-4 (2009) [PubMed]  Article 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM50295948
Synonyms:
2,4-Bis-n-propyl-4,9-dihydro-5-n-propyloxy-2,4,7,9-tetraaza-fluorene-1,3-dione | CHEMBL559990
Type:
Small organic molecule
Emp. Form.:
C18H24N4O3
Mol. Mass.:
344.4082
SMILES:
CCCOc1cncc2[nH]c3c(n(CCC)c(=O)n(CCC)c3=O)c12
Structure:
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