Reaction Details Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM50295949
Substrate
n/a
Meas. Tech.
ChEMBL_578989 (CHEMBL1061438)
Ki
16.8±n/a nM
Citation
 Ishiyama, H; Nakajima, H; Nakata, H; Kobayashi, J Synthesis of hybrid analogues of caffeine and eudistomin D and its affinity for adenosine receptors. Bioorg Med Chem 17:4280-4 (2009) [PubMed]  Article 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM50295949
Synonyms:
2,4-bis-n-propyl-4,9-dihydro-2,4,7,-9-tetraaza-fluorene-1,3-dione | CHEMBL550313
Type:
Small organic molecule
Emp. Form.:
C15H18N4O2
Mol. Mass.:
286.329
SMILES:
CCCn1c2c3ncccc3[nH]c2c(=O)n(CCC)c1=O
Structure:
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