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Target
Cannabinoid receptor 2
Ligand
BDBM50297593
Substrate
n/a
Meas. Tech.
ChEMBL_583691 (CHEMBL1061737)
EC50
403±n/a nM
Citation
 Ryckmans, T; Edwards, MP; Horne, VA; Correia, AM; Owen, DR; Thompson, LR; Tran, I; Tutt, MF; Young, T Rapid assessment of a novel series of selective CB(2) agonists using parallel synthesis protocols: A Lipophilic Efficiency (LipE) analysis. Bioorg Med Chem Lett 19:4406-9 (2009) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM50297593
Synonyms:
2-tert-butyl-1-(cyclopropylmethyl)-5-(methylsulfonyl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine | CHEMBL558857
Type:
Small organic molecule
Emp. Form.:
C15H25N3O2S
Mol. Mass.:
311.443
SMILES:
CC(C)(C)c1nc2CN(CCc2n1CC1CC1)S(C)(=O)=O
Structure:
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