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Target
Peroxisome proliferator-activated receptor alpha
Ligand
BDBM50319263
Substrate
n/a
Meas. Tech.
ChEMBL_633996 (CHEMBL1117969)
EC50
1000±n/a nM
Citation
 Urbahns, K; Woltering, M; Nikolic, S; Pernerstorfer, J; Bischoff, H; Dittrich-Wengenroth, E; Lustig, K Glycine amides as PPARalpha agonists. Bioorg Med Chem Lett 20:3376-9 (2010) [PubMed]  Article 
Target
Name:
Peroxisome proliferator-activated receptor alpha
Synonyms:
NR1C1 | Nuclear receptor subfamily 1 group C member 1 | PPAR | PPAR alpha/gamma | PPAR-alpha | PPARA | PPARA_HUMAN | Peroxisome Proliferator-Activated Receptor alpha | Peroxisome proliferator-activated receptor | Peroxisome proliferator-activated receptor alpha (PPAR alpha)
Type:
Enzyme
Mol. Mass.:
52222.08
Organism:
Homo sapiens (Human)
Description:
Q07869
Residue:
468
Sequence:
MVDTESPLCPLSPLEAGDLESPLSEEFLQEMGNIQEISQSIGEDSSGSFGFTEYQYLGSCPGSDGSVITDTLSPASSPSSVTYPVVPGSVDESPSGALNIECRICGDKASGYHYGVHACEGCKGFFRRTIRLKLVYDKCDRSCKIQKKNRNKCQYCRFHKCLSVGMSHNAIRFGRMPRSEKAKLKAEILTCEHDIEDSETADLKSLAKRIYEAYLKNFNMNKVKARVILSGKASNNPPFVIHDMETLCMAEKTLVAKLVANGIQNKEAEVRIFHCCQCTSVETVTELTEFAKAIPGFANLDLNDQVTLLKYGVYEAIFAMLSSVMNKDGMLVAYGNGFITREFLKSLRKPFCDIMEPKFDFAMKFNALELDDSDISLFVAAIICCGDRPGLLNVGHIEKMQEGIVHVLRLHLQSNHPDDIFLFPKLLQKMADLRQLVTEHAQLVQIIKKTESDAALHPLLQEIYRDMY
  
Inhibitor
Name:
BDBM50319263
Synonyms:
2-(4-((benzyl(2-(2,4-dimethylphenylamino)-2-oxoethyl)amino)methyl)phenoxy)-2-methylpropanoic acid | CHEMBL1085796
Type:
Small organic molecule
Emp. Form.:
C28H32N2O4
Mol. Mass.:
460.5647
SMILES:
Cc1ccc(NC(=O)CN(Cc2ccccc2)Cc2ccc(OC(C)(C)C(O)=O)cc2)c(C)c1
Structure:
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