Reaction Details Report a problem with these data
Target
Sigma non-opioid intracellular receptor 1
Ligand
BDBM50321088
Substrate
n/a
Meas. Tech.
ChEMBL_637393 (CHEMBL1166326)
Ki
0.3±n/a nM
Citation
 Hajipour, AR; Fontanilla, D; Chu, UB; Arbabian, M; Ruoho, AE Synthesis and characterization of N,N-dialkyl and N-alkyl-N-aralkyl fenpropimorph-derived compounds as high affinity ligands for sigma receptors. Bioorg Med Chem 18:4397-404 (2010) [PubMed]  Article 
Target
Name:
Sigma non-opioid intracellular receptor 1
Synonyms:
OPRS1 | SGMR1_CAVPO | SIGMAR1 | Sigma 1-type opioid receptor | Sigma non-opioid intracellular receptor 1 | Sigma-1 receptor | Sigma1-receptor | Sigma1R | Sterol isomerase-like protein
Type:
Protein
Mol. Mass.:
25307.17
Organism:
Cavia porcellus (Guinea pig)
Description:
Q60492
Residue:
223
Sequence:
MQWAVGRRWLWVALFLAAVAVLTQIVWLWLGTQNFVFQREEIAQLARQYAGLDHELAFSKLIVELRRLHPVHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSPRHSGRYWAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPSTLGFALADTVFSTQDFLTLFYTLRVYARALQLELTTYLFGQDP
  
Inhibitor
Name:
BDBM50321088
Synonyms:
CHEMBL1163765 | N-Dibutyl-3-(4-nitrophenyl)ethylamine
Type:
Small organic molecule
Emp. Form.:
C17H28N2O2
Mol. Mass.:
292.4164
SMILES:
CCCCN(CCCC)CCCc1ccc(cc1)[N+]([O-])=O
Structure:
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