Reaction Details Report a problem with these data
Target
Fructose-bisphosphate aldolase
Ligand
BDBM50330438
Substrate
n/a
Meas. Tech.
ChEMBL_684840 (CHEMBL1286070)
Ki
13±n/a nM
Citation
 Daher, R; Coinçon, M; Fonvielle, M; Gest, PM; Guerin, ME; Jackson, M; Sygusch, J; Therisod, M Rational design, synthesis, and evaluation of new selective inhibitors of microbial class II (zinc dependent) fructose bis-phosphate aldolases. J Med Chem 53:7836-42 (2010) [PubMed]  Article 
Target
Name:
Fructose-bisphosphate aldolase
Synonyms:
ALF_HELPY | FBP aldolase | FBPA | Fructose-1,6-bisphosphate aldolase | fba
Type:
PROTEIN
Mol. Mass.:
33770.88
Organism:
Helicobacter pylori
Description:
ChEMBL_684840
Residue:
307
Sequence:
MLVKGNEILLKAHKEGYGVGAFNFVNFEMLNAIFEAGNEENSPLFIQTSEGAIKYMGIDMAVGMVKTMCERYPHIPVALHLDHGTTFESCEKAVKAGFTSVMIDASHHAFEENLELTSKVVKMAHNAGVSVEAELGRLMGIEDNISVDEKDAVLVNPKEAEQFVKESQVDYLAPAIGTSHGAFKFKGEPKLDFERLQEVKRLTNIPLVLHGASAIPDNVRKSYLDAGGDLKGSKGVPFEFLQESVKGGINKVNTDTDLRIAFIAEVRKVANEDKSQFDLRKFFSPAQLALKNVVKERMKLLGSANKI
  
Inhibitor
Name:
BDBM50330438
Synonyms:
3-{hydroxy[(phosphonooxy)acetyl]amino}propyl dihydrogen phosphate | CHEMBL1235276
Type:
Small organic molecule
Emp. Form.:
C5H13NO10P2
Mol. Mass.:
309.1049
SMILES:
ON(CCCOP(O)(O)=O)C(=O)COP(O)(O)=O
Structure:
Search PDB for entries with ligand similarity: