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Target
Phospholipase A2 group V
Ligand
BDBM50333790
Substrate
n/a
Meas. Tech.
ChEMBL_700975 (CHEMBL1648030)
IC50
>1660±n/a nM
Citation
 Mouchlis, VD; Magrioti, V; Barbayianni, E; Cermak, N; Oslund, RC; Mavromoustakos, TM; Gelb, MH; Kokotos, G Inhibition of secreted phospholipases A2 by 2-oxoamides based ona-amino acids: Synthesis, in vitro evaluation and molecular docking calculations. Bioorg Med Chem 19:735-43 (2011) [PubMed]  Article 
Target
Name:
Phospholipase A2 group V
Synonyms:
PA2G5_HUMAN | PLA2G5 | Phospholipase A2 group V | Secretory phospholipase A2, group V (sPLA2-V)
Type:
Protein
Mol. Mass.:
15682.61
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
138
Sequence:
MKGLLPLAWFLACSVPAVQGGLLDLKSMIEKVTGKNALTNYGFYGCYCGWGGRGTPKDGTDWCCWAHDHCYGRLEEKGCNIRTQSYKYRFAWGVVTCEPGPFCHVNLCACDRKLVYCLKRNLRSYNPQYQYFPNILCS
  
Inhibitor
Name:
BDBM50333790
Synonyms:
(S)-4-Methyl-2-palmitamidopentanoic acid | CHEMBL1644551
Type:
Small organic molecule
Emp. Form.:
C22H43NO3
Mol. Mass.:
369.5817
SMILES:
CCCCCCCCCCCCCCCC(=O)N[C@@H](CC(C)C)C(O)=O |r|
Structure:
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