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Target
D-alanyl-D-alanine carboxypeptidase
Ligand
BDBM50337097
Substrate
n/a
Meas. Tech.
ChEMBL_718756 (CHEMBL1681054)
IC50
59000±n/a nM
Citation
 Woon, EC; Zervosen, A; Sauvage, E; Simmons, KJ; Zivec, M; Inglis, SR; Fishwick, CW; Gobec, S; Charlier, P; Luxen, As Structure Guided Development of Potent Reversibly Binding Penicillin Binding Protein Inhibitors ACS Med Chem Lett 2:219-223 (2011) [PubMed]  Article 
Target
Name:
D-alanyl-D-alanine carboxypeptidase
Synonyms:
DAC_ACTSP | dac
Type:
PROTEIN
Mol. Mass.:
54928.46
Organism:
Actinomadura sp. (strain R39)
Description:
ChEMBL_822544
Residue:
538
Sequence:
MKQSSPEPLRPRRTGGRGGARRAAALVTIPLLPMTLLGASPALADASGARLTELREDIDAILEDPALEGAVSGVVVVDTATGEELYSRDGGEQLLPASNMKLFTAAAALEVLGADHSFGTEVAAESAPGRRGEVQDLYLVGRGDPTLSAEDLDAMAAEVAASGVRTVRGDLYADDTWFDSERLVDDWWPEDEPYAYSAQISALTVAHGERFDTGVTEVSVTPAAEGEPADVDLGAAEGYAELDNRAVTGAAGSANTLVIDRPVGTNTIAVTGSLPADAAPVTALRTVDEPAALAGHLFEEALESNGVTVKGDVGLGGVPADWQDAEVLADHTSAELSEILVPFMKFSNNGHAEMLVKSIGQETAGAGTWDAGLVGVEEALSGLGVDTAGLVLNDGSGLSRGNLVTADTVVDLLGQAGSAPWAQTWSASLPVAGESDPFVGGTLANRMRGTAAEGVVEAKTGTMSGVSALSGYVPGPEGELAFSIVNNGHSGPAPLAVQDAIAVRLAEYAGHQAPEGARMMRGPVQGSGELECSWVQAC
  
Inhibitor
Name:
BDBM50337097
Synonyms:
(S)-1-(2-(Propan-2-yl)benzamido)ethaneboronic acid | CHEMBL1672905
Type:
Small organic molecule
Emp. Form.:
C12H18BNO3
Mol. Mass.:
235.087
SMILES:
CC(C)c1ccccc1C(=O)N[C@H](C)B(O)O |r|
Structure:
Search PDB for entries with ligand similarity: