Reaction Details Report a problem with these data
Target
Glutathione S-transferase
Ligand
BDBM50339128
Substrate
n/a
Meas. Tech.
ChEMBL_729209 (CHEMBL1694673)
IC50
29300±n/a nM
Citation
 Sturm, N; Hu, Y; Zimmermann, H; Fritz-Wolf, K; Wittlin, S; Rahlfs, S; Becker, K Compounds structurally related to ellagic acid show improved antiplasmodial activity. Antimicrob Agents Chemother 53:622-30 (2009) [PubMed]  Article 
Target
Name:
Glutathione S-transferase
Synonyms:
GST | GST_PLAF7 | PfGST
Type:
PROTEIN
Mol. Mass.:
24788.28
Organism:
Plasmodium falciparum
Description:
ChEMBL_729209
Residue:
211
Sequence:
MGDNIVLYYFDARGKAELIRLIFAYLGIEYTDKRFGVNGDAFVEFKNFKKEKDTPFEQVPILQIGDLILAQSQAIVRYLSKKYNICGESELNEFYADMIFCGVQDIHYKFNNTNLFKQNETTFLNEDLPKWSGYFEKLLKKNHTNNNNDKYYFVGNNLTYADLAVFNLYDDIETKYPSSLKNFPLLKAHNEFISNLPNIKNYITNRKESVY
  
Inhibitor
Name:
BDBM50339128
Synonyms:
CHEMBL1688543 | Flavellagic acid
Type:
Small organic molecule
Emp. Form.:
C14H6O9
Mol. Mass.:
318.192
SMILES:
Oc1cc2c3c(oc(=O)c4c(O)c(O)c(O)c(oc2=O)c34)c1O
Structure:
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