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Target
Free fatty acid receptor 1
Ligand
BDBM50339463
Substrate
n/a
Meas. Tech.
ChEMBL_736594 (CHEMBL1692323)
EC50
45±n/a nM
Citation
 Sasaki, S; Kitamura, S; Negoro, N; Suzuki, M; Tsujihata, Y; Suzuki, N; Santou, T; Kanzaki, N; Harada, M; Tanaka, Y; Kobayashi, M; Tada, N; Funami, M; Tanaka, T; Yamamoto, Y; Fukatsu, K; Yasuma, T; Momose, Y Design, synthesis, and biological activity of potent and orally available G protein-coupled receptor 40 agonists. J Med Chem 54:1365-78 (2011) [PubMed]  Article 
Target
Name:
Free fatty acid receptor 1
Synonyms:
FFAR1 | FFAR1_HUMAN | G-protein Coupled Receptor 40 | GPR40
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
31473.32
Organism:
Homo sapiens (Human)
Description:
O14842
Residue:
300
Sequence:
MDLPPQLSFGLYVAAFALGFPLNVLAIRGATAHARLRLTPSLVYALNLGCSDLLLTVSLPLKAVEALASGAWPLPASLCPVFAVAHFFPLYAGGGFLAALSAGRYLGAAFPLGYQAFRRPCYSWGVCAAIWALVLCHLGLVFGLEAPGGWLDHSNTSLGINTPVNGSPVCLEAWDPASAGPARFSLSLLLFFLPLAITAFCYVGCLRALARSGLTHRRKLRAAWVAGGALLTLLLCVGPYNASNVASFLYPNLGGSWRKLGLITGAWSVVLNPLVTGYLGRGPGLKTVCAARTQGGKSQK
  
Inhibitor
Name:
BDBM50339463
Synonyms:
3-(4-{[3-(3-Methylphenoxy)benzyl]oxy}phenyl)propanoic Acid | CHEMBL1688460
Type:
Small organic molecule
Emp. Form.:
C23H22O4
Mol. Mass.:
362.4184
SMILES:
Cc1cccc(Oc2cccc(COc3ccc(CCC(O)=O)cc3)c2)c1
Structure:
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