Reaction Details Report a problem with these data
Target
Fe(3+)-Zn(2+) purple acid phosphatase
Ligand
BDBM50343026
Substrate
n/a
Meas. Tech.
ChEMBL_744351 (CHEMBL1772257)
pH
4.9±n/a
Ki
654000±n/a nM
Comments
extracted
Citation
 Mohd-Pahmi, SH; Hussein, WM; Schenk, G; McGeary, RP Synthesis, modelling and kinetic assays of potent inhibitors of purple acid phosphatase. Bioorg Med Chem Lett 21:3092-4 (2011) [PubMed]  Article 
Target
Name:
Fe(3+)-Zn(2+) purple acid phosphatase
Synonyms:
Iron(III)-zinc(II) purple acid phosphatase | PAP | PPAF_PHAVU
Type:
PROTEIN
Mol. Mass.:
52875.57
Organism:
Phaseolus vulgaris
Description:
ChEMBL_560427
Residue:
459
Sequence:
MGVVKGLLALALVLNVVVVSNGGKSSNFVRKTNKNRDMPLDSDVFRVPPGYNAPQQVHITQGDLVGRAMIISWVTMDEPGSSAVRYWSEKNGRKRIAKGKMSTYRFFNYSSGFIHHTTIRKLKYNTKYYYEVGLRNTTRRFSFITPPQTGLDVPYTFGLIGDLGQSFDSNTTLSHYELSPKKGQTVLFVGDLSYADRYPNHDNVRWDTWGRFTERSVAYQPWIWTAGNHEIEFAPEINETEPFKPFSYRYHVPYEASQSTSPFWYSIKRASAHIIVLSSYSAYGRGTPQYTWLKKELRKVKRSETPWLIVLMHSPLYNSYNHHFMEGEAMRTKFEAWFVKYKVDVVFAGHVHAYERSERVSNIAYKITNGLCTPVKDQSAPVYITIGDAGNYGVIDSNMIQPQPEYSAFREASFGHGMFDIKNRTHAHFSWNRNQDGVAVEADSVWFFNRHWYPVDDST
  
Inhibitor
Name:
BDBM50343026
Synonyms:
CHEMBL1771206 | rac-(Butyramido(naphthalen-1-yl)methyl)phosphonic acid
Type:
Small organic molecule
Emp. Form.:
C15H18NO4P
Mol. Mass.:
307.2815
SMILES:
CCCC(=O)NC(c1cccc2ccccc12)P(O)(O)=O
Structure:
Search PDB for entries with ligand similarity: